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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T25487 | Haloperidol decanoate | KD 16,KD-136,KD 136,Neoperidole,Haldol | Others |
Haloperidol decanoate (KD 16) is a typical antipsychotic agent utilized as maintenance treatment for schizophrenia and mood disorders formulated as an ester for intramuscular injection. | |||
T6305 | SNX2112 | SNX-2112,PF 04928473,SNX 2112 | HSP |
SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM. | |||
TP1380 | Galanin (1-16), mouse, porcine, rat | Neuropeptide Y Receptor | |
Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons. | |||
T16334 | NMS-P515 | Others | |
NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity. | |||
TP1317 | Galanin (1-16), mouse, porcine, rat TFA | ||
Galanin (1-16), mouse, porcine, rat is an agonist of the hippocampal galanin receptor, with a Kd of 3 nM. Galanin (1-16), mouse, porcine, rat shows high biological activity on locus coeruleus neurons. | |||
T60556 | SARS-CoV-2-IN-16 | ||
SARS-CoV-2-IN-16 (Compound 12) is a potent inhibitor of SARS-CoV-2 nucleocapsid protein (NPro) with potent antiviral activity (EC50 = 3.69 μM). SARS-CoV-2-IN-16 binds to NPro with a low Kd value of 7.82 μM, which suggest... | |||
T60251 | GID4 Ligand 3 | ||
GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC 50 value of 148.5 μM. GID4 Ligand 3 can be used in the relevant research of cereblon(CRBN) and Von Hippel-Lindau(VHL) [1]. | |||
T61613 | SARS-CoV-2-IN-17 | ||
SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to ... | |||
T77148 | Pegdinetanib | ||
Pegdinetanib (BMS-844203; CT-322) is a selective inhibitor targeting VEGFR-2 (VEGFR), exhibiting dissociation constants (Kd) of 11 nM and 250 nM and half-maximal inhibitory concentrations (IC50) of 16 nM and 240 nM for h... | |||
T36292 | NSC 12 | ||
NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate ... | |||
T11896 | LV-320 | Cysteine Protease | |
LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC 50 of 24.5 μM and a K d of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo. Th... | |||
T36890 | A 410099.1 | ||
High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse ... | |||
T10840L | CM-579 | DNA Methyltransferase , Histone Methyltransferase | |
CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells. | |||
T10840 | CM-579 trihydrochloride (1846570-40-8 free base) | CM-579 trihydrochloride | DNA Methyltransferase |
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells. |